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Fluorescent Site-Specific Integration
Cell Line Development Kit

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Great Bay Bio developed a proprietary AlfaCell platform that applies Site-Specific Integration (SSI) technology and Al-enabled cell selection to accurately insert the target genes into specific “hot spot” within the genome of a host cell line, AlfaCell platform significantly reduces time, manpower, and cost that are associated with the development of high-performance mammalian cell lines.


Case Study

    • Proven High-Titer Expression

    Powered by AI cell selection and SSI technology, AlfaCell has successfully expressed 100+ diverse molecules, achieving titers up to 15 g/L for mAbs, 12 g/L for BsAb, 8.3 g/L for 4-chain BsAb (with 88% correct pairing), and 13.1 g/L for nanobodies.

    • Reliable Correct Pairing

    By accurately integrating genes into genomic “hot spots,” AlfaCell achieves industry-leading correct pairing rates of 84%–100% for complex formats, including bispecific antibodies and IgG.

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