Evaluating hydrophobic groups, charge distribution, and degree of humanization on the surface of antibodies provides early hints and improvements to potential candidate molecules, reduces trial-and-error costs, and accelerates the process of new drug discovery and development.
Biopharmaceuticals are medical drugs produced using biotechnology. They are proteins (including antibodies), nucleic acids (DNA, RNA or antisense oligonucleotides) used for therapeutic purposes. Currently, innovation in biopharmaceuticals require complex knowledge base, ongoing exploration, and expensive processes, amplified by great uncertainties.
Combining AlfaCell® site-specific integration platform for cell line development and AlfaMedX® AI-enabled platform for culture media development, Great Bay Bio provides one-stop bioproduction solutions that achieve robust cell growth, improve recombinant protein yield and ensure high quality for therapeutic antibodies, growth factors, Fc Fusions, and enzyme production.
Cultured meat is genuine animal meat produced by cultivating animal cells directly. This production method eliminates the need to raise and farm animals for food. Cultured meat is made of the same cell types arranged in the same or similar structure as animal tissues, thus replicating the textural and nutritional profiles of conventional meat. AlfaMedX®, an AI-enabled culture media platform, can be used to customize the serum-free medium of cultured meat stem cells.
Industrial enzymes could be used to facilitate industrial processes and catalyze chemical reactions. Enzymes are widely applied to chemical, detergent, textile, food, animal-feed and leather industries, etc. Strain engineering often involves gene expression changes along with gene deletions. Gene expression can be modified experimentally by changing promoters, ribosome binding sites, and plasmid copy numbers or modulating the expression of transcription factors. The latest developments in protein engineering and site-directed evolution have enabled GBB to tailor-make enzymes with new activities for new process conditions.